Do not shake shaking could lead to foaming. To reduce the total reconstitution time needed during preparation, reconstitute all required vials in succession.To ensure dissolution of the cake or powder, gently swirl each vial until complete dissolution of powder occurs. Slowly inject the SWFI, directing the solution onto the inside wall of the vial to minimize foaming. IV Bolus Preparation: Determine total number of vials required (see Table 1).ġ00 mg vials: Reconstitute the 100 mg vial of ANDEXXA with 10 mL of Sterile Water for Injection, USP (SWFI) Or 200 mg vials: Reconstitute the 200 mg vial of ANDEXXA with 20 mL of SWFI.Use a 20-mL (or larger) syringe and 20-gauge (or higher) needle. Reconstituted ANDEXXA in IV bags is stable at room temperature for up to eight hours.Reconstituted ANDEXXA in vials is stable at room temperature for up to eight hours, or may be stored for up to 24 hours at 2☌ to 8☌.The reconstituted solution contains coagulation factor Xa (recombinant), inactivated-zhzo at a concentration of 10 mg/mL.(reconstituted solution is placed into an empty polyolefin or polyvinyl chloride IV bag with a volume of 250 mL or less.)ġ00 mg vials: Reconstitute the 100 mg vial of ANDEXXA with 10 mL of Sterile Water for Injection, USP (SWFI) Or 200 mg vials: Reconstitute the 200 mg vial of ANDEXXA with 20 mL of SWFI. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER.ĭrug UPDATES: P ACKAGE INSERT Please read the disclaimer carefully BEFORE accessing or using this site.

nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material. The authors make no claims of the accuracy of the information on ANDEXXA, andexanet or any other information contained herein and these suggested doses are not a substitute for clinical judgment. PRESCRIBING HIGHLIGHTS: Please see package insert for additional information and possible updates to ensure safe and effective use of this medication.

Andexxa drug